| Vulpes Life Sciences Fund |
618,542,844 |
£1,175,231 |
| Pentwater Capital Management LP |
500,000,000 |
£950,000 |
| Unicorn Asset Management Limited |
278,464,859 |
£529,083 |
| Sankofa Strategic Equity Fund Limited |
211,855,049 |
£402,525 |
| Trafalgar Capital Management (HK) Limited |
130,316,163 |
£247,601 |
| Arbuthnot Latham (Nominees) Limited |
74,250,303 |
£141,076 |
| William Henry Salomon |
60,000,000 |
£114,000 |
| Odey Funds |
26,945,092 |
£51,196 |
| Lombard Odier Asset Management (Europe) Limited |
15,568,816 |
£29,581 |
| Dr Yavuz Ahiska |
10,577,600 |
£20,097 |
| Seneca Partners Limited |
9,978,822 |
£18,960 |
| Armistice Capital LLC |
7,791,803 |
£14,804 |
| Investec Wealth & Investment Limited |
7,319,886 |
£13,908 |
| The Chancellor, Masters and Scholars of the University of Oxford |
5,724,476 |
£10,876 |
| GL Healthcare Investment L.P. |
4,688,000 |
£8,907 |
| PHILIPPA MARGARET HOYER MILLAR |
4,473,140 |
£8,499 |
| The Goldman Sachs Group, Inc. |
4,404,088 |
£8,368 |